A Convenient Procedure for Friedlander Synthesis of Quinoline Derivatives Catalyzed by Zirconium Dodecylphosphonate as an Efficient and Reusable Catalyst

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Abstract:

2-Amino-substituted ketones react with α-methylene ketones under solvent-free conditions at 90 °C in thepresence of a catalytic amount of zirconium dodecylphosphonate to create the corresponding quinolinesin excellent yields. This procedure recommends numerous advantages such as easy work-up, use of mild,reusable and safe catalyst, short reaction timeand high yields. The new compounds have been characterizedby 1H-NMR, 13C-NMR, mass and elemental analysis data.

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Journal title

volume 3  issue 2

pages  195- 199

publication date 2015-08-01

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